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Monofluorophosphate Blocks Internal Polysaccharide Synthesis in Streptococcus mutans

Streptococcus mutans is the leading cause of dental caries worldwide by accumulating a glycogen-like internal polysaccharide (IPS) that contributes to cariogenicity when sugars are in excess. Sodium monofluorophosphate (MFP) is an active anticariogenic compound in toothpastes. Herein, we show that M...

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Detalles Bibliográficos
Autores principales: Demonte, Ana M., Asencion Diez, Matias D., Naleway, Conrad, Iglesias, Alberto A., Ballicora, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268466/
https://www.ncbi.nlm.nih.gov/pubmed/28125652
http://dx.doi.org/10.1371/journal.pone.0170483