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Differences in AMY1 Gene Copy Numbers Derived from Blood, Buccal Cells and Saliva Using Quantitative and Droplet Digital PCR Methods: Flagging the Pitfall
INTRODUCTION: The human salivary (AMY1) gene, encoding salivary α-amylase, has variable copy number variants (CNVs) in the human genome. We aimed to determine if real-time quantitative polymerase chain reaction (qPCR) and the more recently available Droplet Digital PCR (ddPCR) can provide a precise...
Autores principales: | Ooi, Delicia Shu Qin, Tan, Verena Ming Hui, Ong, Siong Gim, Chan, Yiong Huak, Heng, Chew Kiat, Lee, Yung Seng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268653/ https://www.ncbi.nlm.nih.gov/pubmed/28125683 http://dx.doi.org/10.1371/journal.pone.0170767 |
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