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Allosteric Regulation in the Ligand Binding Domain of Retinoic Acid Receptorγ

Retinoic acid (RA) plays key roles in cell differentiation and growth arrest through nuclear retinoic acid receptors (RARs), which are ligand-dependent transcription factors. While the main trigger of RAR activation is the binding of RA, phosphorylation of the receptors has also emerged as an import...

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Detalles Bibliográficos
Autores principales: Chebaro, Yassmine, Sirigu, Serena, Amal, Ismail, Lutzing, Régis, Stote, Roland H., Rochette-Egly, Cécile, Rochel, Natacha, Dejaegere, Annick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268703/
https://www.ncbi.nlm.nih.gov/pubmed/28125680
http://dx.doi.org/10.1371/journal.pone.0171043