Identification of MiR-21-5p as a Functional Regulator of Mesothelin Expression Using MicroRNA Capture Affinity Coupled with Next Generation Sequencing

MicroRNAs (miRNAs) are small non-coding RNAs that regulate mRNA expression mainly by silencing target transcripts via binding to miRNA recognition elements (MREs) in the 3’untranslated region (3’UTR). The identification of bona fide targets is challenging for researchers working on the functional as...

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Detalles Bibliográficos
Autores principales: De Santi, Chiara, Vencken, Sebastian, Blake, Jonathon, Haase, Bettina, Benes, Vladimir, Gemignani, Federica, Landi, Stefano, Greene, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268774/
https://www.ncbi.nlm.nih.gov/pubmed/28125734
http://dx.doi.org/10.1371/journal.pone.0170999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268774/
https://www.ncbi.nlm.nih.gov/pubmed/28125734
http://dx.doi.org/10.1371/journal.pone.0170999

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