Effect of Sustained PDGF Non-Viral Gene Delivery on Repair of Tooth-Supporting Bone Defects

Recombinant human platelet-derived growth factor-BB (rhPDGF-BB) promotes soft tissue and bone healing, and is FDA-approved for treatment of diabetic ulcers and periodontal defects. The short half-life of topical rhPDGF-BB protein application necessitates bolus, high-dose delivery. Gene therapy enabl...

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Detalles Bibliográficos
Autores principales: Plonka, Alexandra B., Khorsand, Behnoush, Yu, Ning, Sugai, James V., Salem, Aliasger K., Giannobile, William V., Elangovan, Satheesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269540/
https://www.ncbi.nlm.nih.gov/pubmed/27824330
http://dx.doi.org/10.1038/gt.2016.73

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269540/
https://www.ncbi.nlm.nih.gov/pubmed/27824330
http://dx.doi.org/10.1038/gt.2016.73

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