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Effect of Sustained PDGF Non-Viral Gene Delivery on Repair of Tooth-Supporting Bone Defects

Recombinant human platelet-derived growth factor-BB (rhPDGF-BB) promotes soft tissue and bone healing, and is FDA-approved for treatment of diabetic ulcers and periodontal defects. The short half-life of topical rhPDGF-BB protein application necessitates bolus, high-dose delivery. Gene therapy enabl...

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Detalles Bibliográficos
Autores principales:	Plonka, Alexandra B., Khorsand, Behnoush, Yu, Ning, Sugai, James V., Salem, Aliasger K., Giannobile, William V., Elangovan, Satheesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269540/ https://www.ncbi.nlm.nih.gov/pubmed/27824330 http://dx.doi.org/10.1038/gt.2016.73

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