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Functional characterization of NES and GES responsible for the biosynthesis of (E)-nerolidol and (E,E)-geranyllinalool in Tripterygium wilfordii

Triptolide and celastrol, two principal bioactive compounds in Tripterygium wilfordii, are produced from geranylgeranyl diphosphate (GGPP) and farnesyl diphosphate ((E,E)-FPP) through terpenoid biosynthesis pathway. However, little is known about T. wilfordii terpene synthases which could competitiv...

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Detalles Bibliográficos
Autores principales: Su, Ping, Hu, Tianyuan, Liu, Yujia, Tong, Yuru, Guan, Hongyu, Zhang, Yifeng, Zhou, Jiawei, Huang, Luqi, Gao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269589/
https://www.ncbi.nlm.nih.gov/pubmed/28128232
http://dx.doi.org/10.1038/srep40851