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Scalable Synthesis of (−)-Thapsigargin
[Image: see text] Total syntheses of the complex, highly oxygenated sesquiterpenes thapsigargin (1) and nortrilobolide (2) are presented. Access to analogues of these promising bioactive natural products has been limited to tedious isolation and semisynthetic efforts. Elegant prior total syntheses d...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269647/ https://www.ncbi.nlm.nih.gov/pubmed/28149952 http://dx.doi.org/10.1021/acscentsci.6b00313 |