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Periostin Upregulates Wnt/β-Catenin Signaling to Promote the Osteogenesis of CTLA4-Modified Human Bone Marrow-Mesenchymal Stem Cells

The enhanced osteogenesis of mesenchymal stem cells (MSCs) modified by expression of cytotoxic T lymphocyte-associated antigen 4 (CTLA4) has been shown in previous studies, but the mechanism remains unknown. Here we found that the bone repair effect of CTLA4-modified MSCs in demineralized bone matri...

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Detalles Bibliográficos
Autores principales: Zhang, Fei, Luo, Keyu, Rong, Zhigang, Wang, Zhengdong, Luo, Fei, Zhang, Zehua, Sun, Dong, Dong, Shiwu, Xu, Jianzhong, Dai, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269711/
https://www.ncbi.nlm.nih.gov/pubmed/28128364
http://dx.doi.org/10.1038/srep41634