Cargando…

Epigallocatechin-3-gallate preferentially induces aggregation of amyloidogenic immunoglobulin light chains

Antibody light chain amyloidosis is a rare disease caused by fibril formation of secreted immunoglobulin light chains (LCs). The huge variety of antibody sequences puts a serious challenge to drug discovery. The green tea polyphenol epigallocatechin-3-gallate (EGCG) is known to interfere with fibril...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hora, Manuel, Carballo-Pacheco, Martin, Weber, Benedikt, Morris, Vanessa K., Wittkopf, Antje, Buchner, Johannes, Strodel, Birgit, Reif, Bernd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269747/ https://www.ncbi.nlm.nih.gov/pubmed/28128355 http://dx.doi.org/10.1038/srep41515

Ejemplares similares

Green Tea Polyphenol Epigallocatechin-Gallate in Amyloid Aggregation and Neurodegenerative Diseases
por: Fernandes, Luiza, et al.
Publicado: (2021)

Interplay between epigallocatechin-3-gallate and ionic strength during amyloid aggregation
por: Ziaunys, Mantas, et al.
Publicado: (2021)

Skin Protective Effect of Epigallocatechin Gallate
por: Kim, Eunji, et al.
Publicado: (2018)

Role of Epigallocatechin Gallate in Glucose, Lipid, and Protein Metabolism and L-Theanine in the Metabolism-Regulatory Effects of Epigallocatechin Gallate
por: Lin, Ling, et al.
Publicado: (2021)

Interaction of quercetin and epigallocatechin gallate (EGCG) aggregates with pancreatic lipase under simplified intestinal conditions
por: Bustos, Atma-Sol, et al.
Publicado: (2020)

Epigallocatechin Gallate Nanodelivery Systems for Cancer Therapy
por: Granja, Andreia, et al.
Publicado: (2016)

Food-Grade Encapsulation Systems for (−)-Epigallocatechin Gallate
por: Shi, Meng, et al.
Publicado: (2018)

Therapeutic Potential of Epigallocatechin Gallate Nanodelivery Systems
por: Granja, Andreia, et al.
Publicado: (2017)

Effect of Epigallocatechin Gallate on Viability of Kudoa septempunctata
por: Shin, Sang Phil, et al.
Publicado: (2020)

Effects of epigallocatechin-3-gallate combined with ascorbic acid and glycerol on the stability and uric acid-lowering activity of epigallocatechin-3-gallate
por: Xie, Qianjin, et al.
Publicado: (2021)

Epigallocatechin-3-gallate and Epigallocatechin-3-O-(3-O-methyl)-gallate Enhance the Bonding Stability of an Etch-and-Rinse Adhesive to Dentin
por: Yu, Hao-Han, et al.
Publicado: (2017)

Identification of EZH2 as Cancer Stem Cell Marker in Clear Cell Renal Cell Carcinoma and the Anti-Tumor Effect of Epigallocatechin-3-Gallate (EGCG)
por: Lyu, Chen, et al.
Publicado: (2022)

Aggregation of an Amyloidogenic Peptide on Gold Surfaces
por: Cheung, David L.
Publicado: (2023)

Effects of (-)-epigallocatechin gallate on RPE cell migration and adhesion
por: Chan, Chi-Ming, et al.
Publicado: (2010)

Broad inhibition of plasmodium falciparum cytoadherence by (+)-epigallocatechin gallate
por: Patil, Pradeep R, et al.
Publicado: (2011)

Potential neuroprotective properties of epigallocatechin-3-gallate (EGCG)
por: Singh, Neha Atulkumar, et al.
Publicado: (2016)

Inhibitory Effects of (−)-Epigallocatechin-3-gallate on Esophageal Cancer
por: Wang, Liu-Xiang, et al.
Publicado: (2019)

The Effect of Ultrasound, Oxygen and Sunlight on the Stability of (−)-Epigallocatechin Gallate
por: Zeng, Jiajun, et al.
Publicado: (2018)

Melatonin and (−)-Epigallocatechin-3-Gallate: Partners in Fighting Cancer
por: Zhang, Lingyun, et al.
Publicado: (2019)

Anticancer effects and molecular mechanisms of epigallocatechin-3-gallate
por: Min, Kyoung-jin, et al.
Publicado: (2014)

Effects of Epigallocatechin-3-Gallate on Autophagic Lipolysis in Adipocytes
por: Kim, Sang-Nam, et al.
Publicado: (2017)

Preclinical Activities of Epigallocatechin Gallate in Signaling Pathways in Cancer
por: Sharifi-Rad, Mehdi, et al.
Publicado: (2020)

Epigallocatechin-3-Gallate as a Novel Vaccine Adjuvant
por: Cheong, Yucheol, et al.
Publicado: (2021)

The potential of epigallocatechin gallate in the chemoprevention and therapy of hepatocellular carcinoma
por: Li, Dongming, et al.
Publicado: (2023)

Zeolites with Divalent Ions as Carriers in the Delivery of Epigallocatechin Gallate
por: Sandomierski, Mariusz, et al.
Publicado: (2023)

In Vitro Evaluation of the Antiviral Activity of the Synthetic Epigallocatechin Gallate Analog-Epigallocatechin Gallate (EGCG) Palmitate against Porcine Reproductive and Respiratory Syndrome Virus
por: Zhao, Chunjian, et al.
Publicado: (2014)

Epigallocatechin gallate (EGCG) reduces the intensity of pancreatic amyloid fibrils in human islet amyloid polypeptide (hIAPP) transgenic mice
por: Franko, Andras, et al.
Publicado: (2018)

Molecular mechanism of amyloidogenic mutations in hypervariable regions of antibody light chains
por: Rottenaicher, Georg J., et al.
Publicado: (2021)

Insights into the Effect of Curcumin and (–)-Epigallocatechin-3-Gallate on the Aggregation of Aβ(1–40) Monomers by Means of Molecular Dynamics
por: Tavanti, Francesco, et al.
Publicado: (2020)

Antibacterial and Antifungal Activities of New Acylated Derivatives of Epigallocatechin Gallate
por: Matsumoto, Yoshimi, et al.
Publicado: (2012)

Molecular Interactions between (−)-Epigallocatechin Gallate Analogs and Pancreatic Lipase
por: Wang, Shihui, et al.
Publicado: (2014)

In Vitro Toxicity of Epigallocatechin Gallate in Rat Liver Mitochondria and Hepatocytes
por: Kucera, Otto, et al.
Publicado: (2015)

(−)-Epigallocatechin-3-gallate induces secretion of anorexigenic gut hormones
por: Song, Won-Young, et al.
Publicado: (2015)

Neuroprotective Activity of (−)-Epigallocatechin Gallate against Lipopolysaccharide-Mediated Cytotoxicity
por: Liu, Jin-Biao, et al.
Publicado: (2016)

Anticancer activities of epigallocatechin-3-gallate against cholangiocarcinoma cells
por: Kwak, Tae Won, et al.
Publicado: (2016)

Effects of epigallocatechin-3-gallate on bovine oocytes matured in vitro
por: Huang, Ziqiang, et al.
Publicado: (2018)

Dietary Copper Reduces the Hepatotoxicity of (−)-Epigallocatechin-3-Gallate in Mice
por: Kaleri, Najeeb Ahmed, et al.
Publicado: (2017)

Effects of Epigallocatechin Gallate on the Stability of Epicatechin in a Photolytic Process
por: Huang, Shiuh-Tsuen, et al.
Publicado: (2019)

Epigallocatechin-3-Gallate Reduces Fat Accumulation in Caenorhabditis elegans
por: Liu, Jinning, et al.
Publicado: (2018)

Epigallocatechin-3-gallate counters cisplatin toxicity of rat testes
por: Fouad, Amr A., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_o82nnbgjcb7kho5pm9s8056pmr