Attachment of class B CpG ODN onto DOTAP/DC-chol liposome in nasal vaccine formulations augments antigen-specific immune responses in mice

BACKGROUND: To overcome infectious diseases, the development of mucosal vaccines would be an effective strategy, since mucosal surfaces are the entry site for most pathogens. In general, protein antigens show inherently poor immunogenicity when administered by the mucosal route. Therefore, co-admini...

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Detalles Bibliográficos
Autores principales: Tada, Rui, Muto, Shoko, Iwata, Tomoko, Hidaka, Akira, Kiyono, Hiroshi, Kunisawa, Jun, Aramaki, Yukihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270218/
https://www.ncbi.nlm.nih.gov/pubmed/28126014
http://dx.doi.org/10.1186/s13104-017-2380-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270218/
https://www.ncbi.nlm.nih.gov/pubmed/28126014
http://dx.doi.org/10.1186/s13104-017-2380-8

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