Inhibitory effect of a novel peptide, H-RN, on keratitis induced by LPS or poly(I:C) in vitro and in vivo via suppressing NF-κB and MAPK activation

BACKGROUND: Keratitis is a common cause of blindness. Current anti-inflammatory drugs used in keratitis have profound side effects. Small peptides derived from endogenous proteins potentially display both desired efficiency and safety. We identified an 11-amino-acid peptide, H-RN, from hepatocyte gr...

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Detalles Bibliográficos
Autores principales: Zhu, Shaopin, Xu, Xun, Wang, Lili, Su, Li, Gu, Qing, Wei, Fang, Liu, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270222/
https://www.ncbi.nlm.nih.gov/pubmed/28125988
http://dx.doi.org/10.1186/s12967-017-1121-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270222/
https://www.ncbi.nlm.nih.gov/pubmed/28125988
http://dx.doi.org/10.1186/s12967-017-1121-z

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