Pembrolizumab: Role of Modeling and Simulation in Bringing a Novel Immunotherapy to Patients With Melanoma

Recently, immunotherapy has yielded promising results in several cancer types. Contrary to the established classical chemotherapy‐dosing paradigm, a maximum tolerated dose approach does not always produce better clinical outcomes for novel targeted therapies, as their efficacy is frequently robust a...

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Detalles Bibliográficos
Autores principales: de Greef, R, Elassaiss‐Schaap, J, Chatterjee, M, Turner, DC, Ahamadi, M, Forman, M, Cutler, D, de Alwis, DP, Kondic, A, Stone, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270292/
https://www.ncbi.nlm.nih.gov/pubmed/27653180
http://dx.doi.org/10.1002/psp4.12131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270292/
https://www.ncbi.nlm.nih.gov/pubmed/27653180
http://dx.doi.org/10.1002/psp4.12131

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