Cargando…

Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/Akt signaling pathway in gastric cancer

BACKGROUND: Gastric cancer is one of the major causes of cancer-related mortality worldwide. Most of patients presenting with inoperable gastric cancers rely on systemic chemotherapy for prolongation of survival. Doxorubicin (DOX) is one of the important agents against gastric cancer. Acquired DOX-r...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Jiahui, Liu, Deying, Niu, Huilin, Zhu, Guifang, Xu, Yangwei, Ye, Danli, Li, Jian, Zhang, Qingling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270306/
https://www.ncbi.nlm.nih.gov/pubmed/28126034
http://dx.doi.org/10.1186/s13046-016-0487-8