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What’s in a name? Context-dependent significance of ‘global’ methylation measures in human health and disease

The study of DNA methylation in development and disease has ‘exploded’ as a field in recent years, with three major classes of measurement now routine. These encompass (i) locus-specific, (ii) genome-scale/wide and (iii) ‘global’ methylation approaches. Measures of global methylation refer to the le...

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Detalles Bibliográficos
Autores principales: Vryer, Regan, Saffery, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270354/
https://www.ncbi.nlm.nih.gov/pubmed/28149330
http://dx.doi.org/10.1186/s13148-017-0311-0