Conversion of Fibroblasts to Neural Cells by p53 Depletion

Conversion from fibroblasts to neurons has recently been successfully induced. However, the underlying mechanisms are poorly understood. Here, we find that depletion of p53 alone converts fibroblasts into all three major neural lineages. The induced neuronal cells express multiple neuron-specific pr...

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Detalles Bibliográficos
Autores principales: Zhou, Di, Zhang, Zhen, He, Li-Ming, Du, Juan, Zhang, Fan, Sun, Chong-Kui, Zhou, Yu, Wang, Xiao-Wei, Lin, Ge, Song, Ke-Ming, Wu, Ling-Gang, Yang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270413/
https://www.ncbi.nlm.nih.gov/pubmed/25533343
http://dx.doi.org/10.1016/j.celrep.2014.11.040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270413/
https://www.ncbi.nlm.nih.gov/pubmed/25533343
http://dx.doi.org/10.1016/j.celrep.2014.11.040

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