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Template-based intervention in Boolean network models of biological systems

MOTIVATION: A grand challenge in the modeling of biological systems is the identification of key variables which can act as targets for intervention. Boolean networks are among the simplest of models, yet they have been shown to adequately model many of the complex dynamics of biological systems. In...

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Detalles Bibliográficos
Autores principales: Verdicchio, Michael P, Kim, Seungchan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270454/
https://www.ncbi.nlm.nih.gov/pubmed/28194161
http://dx.doi.org/10.1186/s13637-014-0011-4