Cargando…

Mixed T Cell Chimerism After Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia Using an Alemtuzumab-Containing Regimen Is Shaped by Persistence of Recipient CD8 T Cells

Prevention of graft-versus-host disease (GVHD) is paramount for allogeneic hematopoietic stem cell transplantation (HSCT) to treat nonmalignant diseases. We previously reported that allogeneic HSCT for severe aplastic anemia (SAA) using the fludarabine, cyclophosphamide, and alemtuzumab (Campath-1H)...

Descripción completa

Detalles Bibliográficos
Autores principales: Grimaldi, Francesco, Potter, Victoria, Perez-Abellan, Pilar, Veluchamy, John P., Atif, Muhammad, Grain, Rosemary, Sen, Monica, Best, Steven, Lea, Nicholas, Rice, Carmel, Pagliuca, Antonio, Mufti, Ghulam J., Marsh, Judith C.W., Barber, Linda D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Carden Jennings Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270460/
https://www.ncbi.nlm.nih.gov/pubmed/27816648
http://dx.doi.org/10.1016/j.bbmt.2016.11.003