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Visualization of newly synthesized neuronal RNA in vitro and in vivo using click-chemistry

The neuronal transcriptome changes dynamically to adapt to stimuli from the extracellular and intracellular environment. In this study, we adapted for the first time a click chemistry technique to label the newly synthesized RNA in cultured hippocampal neurons and intact larval zebrafish brain. Ethy...

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Detalles Bibliográficos
Autores principales: Akbalik, Güney, Langebeck-Jensen, Kasper, Tushev, Georgi, Sambandan, Sivakumar, Rinne, Jennifer, Epstein, Irina, Cajigas, Iván, Vlatkovic, Irena, Schuman, Erin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270548/
https://www.ncbi.nlm.nih.gov/pubmed/27801616
http://dx.doi.org/10.1080/15476286.2016.1251541