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An ELISA DYRK1A non-radioactive kinase assay suitable for the characterization of inhibitors

The DYRK1A (dual specificity tyrosine phosphorylation-regulated kinase 1A) gene encodes a proline-directed Ser/Thr kinase. Elevated expression and/or altered distribution of the kinase have been implicated in the neurological impairments associated with Down syndrome (DS) and Alzheimer’s disease (AD...

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Detalles Bibliográficos
Autores principales: Liu, Yong, Adayev, Tatyana, Hwang, Yu-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270589/
https://www.ncbi.nlm.nih.gov/pubmed/28163906
http://dx.doi.org/10.12688/f1000research.10582.2