Cargando…
An ELISA DYRK1A non-radioactive kinase assay suitable for the characterization of inhibitors
The DYRK1A (dual specificity tyrosine phosphorylation-regulated kinase 1A) gene encodes a proline-directed Ser/Thr kinase. Elevated expression and/or altered distribution of the kinase have been implicated in the neurological impairments associated with Down syndrome (DS) and Alzheimer’s disease (AD...
Autores principales: | Liu, Yong, Adayev, Tatyana, Hwang, Yu-Wen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270589/ https://www.ncbi.nlm.nih.gov/pubmed/28163906 http://dx.doi.org/10.12688/f1000research.10582.2 |
Ejemplares similares
-
Abnormalities of DYRK1A-Cytoskeleton Complexes in the Blood Cells as Potential Biomarkers of Alzheimer’s Disease
por: Dowjat, Karol, et al.
Publicado: (2019) -
Development of a sensitive non-radioactive protein kinase assay and its application for detecting DYRK activity in Xenopus laevis oocytes
por: Lilienthal, Eva, et al.
Publicado: (2010) -
Optimization and validation of a DYRK1A TR-FRET assay for high-throughput screening
por: Tarpley, Michael, et al.
Publicado: (2021) -
Complementary non-radioactive assays for investigation of human flap endonuclease 1 activity
por: Dorjsuren, Dorjbal, et al.
Publicado: (2011) -
A versatile non-radioactive assay for DNA methyltransferase activity and DNA binding
por: Frauer, Carina, et al.
Publicado: (2009)