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Rapamycin Eye Drops Suppress Lacrimal Gland Inflammation In a Murine Model of Sjögren's Syndrome

PURPOSE: To evaluate the efficacy of topical rapamycin in treating autoimmune dacryoadenitis in a mouse model of Sjögren's syndrome. METHODS: We developed rapamycin in a poly(ethylene glycol)-distearoyl phosphatidylethanolamine (PEG-DSPE) micelle formulation to maintain solubility. Rapamycin or...

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Detalles Bibliográficos
Autores principales:	Shah, Mihir, Edman, Maria C., Reddy Janga, Srikanth, Yarber, Frances, Meng, Zhen, Klinngam, Wannita, Bushman, Jonathan, Ma, Tao, Liu, Siyu, Louie, Stan, Mehta, Arjun, Ding, Chuanqing, MacKay, J. Andrew, Hamm-Alvarez, Sarah F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2017
Materias:	Cornea
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270623/ https://www.ncbi.nlm.nih.gov/pubmed/28122086 http://dx.doi.org/10.1167/iovs.16-19159

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