Age-related changes in the gene expression profile of antigen-specific mouse CD8+ T cells can be partially reversed by blockade of the BTLA/CD160 pathways during vaccination

We analyzed gene expression profiles of young and aged mouse CD8(+) T cells specific for the nucleoprotein (NP) of influenza A/PR8/34 virus. CD8(+) T cells were stimulated either by the NP antigen expressed in its native form or fused into the herpes virus (HSV)-1 glycoprotein D (gD) protein, which...

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Detalles Bibliográficos
Autores principales: Dawany, Noor, Parzych, Elizabeth M, Showe, Louise C, Ertl, Hildegund CJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270668/
https://www.ncbi.nlm.nih.gov/pubmed/27922818
http://dx.doi.org/10.18632/aging.101105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270668/
https://www.ncbi.nlm.nih.gov/pubmed/27922818
http://dx.doi.org/10.18632/aging.101105

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