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RelA NF-κB subunit activation as a therapeutic target in diffuse large B-cell lymphoma

It has been well established that nuclear factor kappa-B (NF-κB) activation is important for tumor cell growth and survival. RelA/p65 and p50 are the most common NF-κB subunits and involved in the classical NF-κB pathway. However, the prognostic and biological significance of RelA/p65 is equivocal i...

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Detalles Bibliográficos
Autores principales: Zhang, Mingzhi, Xu-Monette, Zijun Y., Li, Ling, Manyam, Ganiraju C., Visco, Carlo, Tzankov, Alexandar, Wang, Jing, Montes-Moreno, Santiago, Dybkaer, Karen, Chiu, April, Orazi, Attilio, Zu, Youli, Bhagat, Govind, Richards, Kristy L., Hsi, Eric D., Choi, William W.L., Han van Krieken, J., Huh, Jooryung, Ponzoni, Maurilio, Ferreri, Andrés J.M., Møller, Michael B., Parsons, Ben M., Winter, Jane N., Piris, Miguel A., Jeffrey Medeiros, L., Pham, Lan V., Young, Ken H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270671/
https://www.ncbi.nlm.nih.gov/pubmed/27941215
http://dx.doi.org/10.18632/aging.101121