Altered stoichiometry and nuclear delocalization of NonO and PSF promote cellular senescence

While cellular senescence is a critical mechanism to prevent malignant transformation of potentially mutated cells, persistence of senescent cells can also promote cancer and aging phenotypes. NonO/p54nrb and PSF are multifunctional hnRNPs typically found as a complex exclusively within the nuclei o...

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Detalles Bibliográficos
Autores principales: Huang, Ching-Jung, Das, Utsab, Xie, Weijun, Ducasse, Miryam, Tucker, Haley O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270673/
https://www.ncbi.nlm.nih.gov/pubmed/27992859
http://dx.doi.org/10.18632/aging.101125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270673/
https://www.ncbi.nlm.nih.gov/pubmed/27992859
http://dx.doi.org/10.18632/aging.101125

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