Accumulation of spontaneous γH2AX foci in long-term cultured mesenchymal stromal cells

Expansion of mesenchymal stromal/stem cells (MSCs) used in clinical practices may be associated with accumulation of genetic instability. Understanding temporal and mechanistic aspects of this process is important for improving stem cell therapy protocols. We used γH2AX foci as a marker of a genetic...

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Detalles Bibliográficos
Autores principales: Pustovalova, Margarita, Grekhova, Anna, Astrelina, Tatiana, Nikitina, Viktoria, Dobrovolskaya, Ekaterina, Suchkova, Yulia, Kobzeva, Irina, Usupzhanova, Darya, Vorobyeva, Natalia, Samoylov, Aleksandr, Bushmanov, Andrey, Ozerov, Ivan V., Zhavoronkov, Alex, Leonov, Sergey, Klokov, Dmitry, Osipov, Andreyan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270682/
https://www.ncbi.nlm.nih.gov/pubmed/27959319
http://dx.doi.org/10.18632/aging.101142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270682/
https://www.ncbi.nlm.nih.gov/pubmed/27959319
http://dx.doi.org/10.18632/aging.101142

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