Blood Trimethylamine-N-Oxide Originates from Microbiota Mediated Breakdown of Phosphatidylcholine and Absorption from Small Intestine

Elevated serum trimethylamine-N-oxide (TMAO) was previously reported to be associated with an elevated risk for cardiovascular events. TMAO originates from the microbiota-dependent breakdown of food-derived phosphatidylcholine (PC) to trimethylamine (TMA), which is oxidized by hepatic flavin-contain...

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Detalles Bibliográficos
Autores principales: Stremmel, Wolfgang, Schmidt, Kathrin V., Schuhmann, Vera, Kratzer, Frank, Garbade, Sven F., Langhans, Claus-Dieter, Fricker, Gert, Okun, Jürgen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271338/
https://www.ncbi.nlm.nih.gov/pubmed/28129384
http://dx.doi.org/10.1371/journal.pone.0170742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271338/
https://www.ncbi.nlm.nih.gov/pubmed/28129384
http://dx.doi.org/10.1371/journal.pone.0170742

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