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The NLRP3 and Pyrin Inflammasomes: Implications in the Pathophysiology of Autoinflammatory Diseases

Inflammasomes are multiprotein complexes that critically control different aspects of innate and adaptive immunity. Among them we could highlight the release of pro-inflammatory cytokines that induce and maintain the inflammatory response. Usually, inflammasomes result from oligomerization of a nucl...

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Detalles Bibliográficos
Autores principales: de Torre-Minguela, Carlos, Mesa del Castillo, Pablo, Pelegrín, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271383/
https://www.ncbi.nlm.nih.gov/pubmed/28191008
http://dx.doi.org/10.3389/fimmu.2017.00043