Phenotypic outcomes in Mouse and Human Foxc1 dependent Dandy-Walker cerebellar malformation suggest shared mechanisms

FOXC1 loss contributes to Dandy-Walker malformation (DWM), a common human cerebellar malformation. Previously, we found that complete Foxc1 loss leads to aberrations in proliferation, neuronal differentiation and migration in the embryonic mouse cerebellum (Haldipur et al., 2014). We now demonstrate...

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Detalles Bibliográficos
Autores principales: Haldipur, Parthiv, Dang, Derek, Aldinger, Kimberly A, Janson, Olivia K, Guimiot, Fabien, Adle-Biasette, Homa, Dobyns, William B, Siebert, Joseph R, Russo, Rosa, Millen, Kathleen J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271606/
https://www.ncbi.nlm.nih.gov/pubmed/28092268
http://dx.doi.org/10.7554/eLife.20898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271606/
https://www.ncbi.nlm.nih.gov/pubmed/28092268
http://dx.doi.org/10.7554/eLife.20898

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