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Immune characteristics study of AG490, a signal pathway inhibitor, in EAE model mice
Multiple sclerosis (MS) is an autoimmune disease characterized by demyelination, axonal damage and progressive neurologic dysfunction in central nervous system (CNS). Many evidences show that B cells play an important role in the pathogenesis of MS. Follicular helper T cells (Tfh) secrete IL-21 to p...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5272958/ https://www.ncbi.nlm.nih.gov/pubmed/28149160 http://dx.doi.org/10.1016/j.sjbs.2016.08.015 |