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Immune characteristics study of AG490, a signal pathway inhibitor, in EAE model mice

Multiple sclerosis (MS) is an autoimmune disease characterized by demyelination, axonal damage and progressive neurologic dysfunction in central nervous system (CNS). Many evidences show that B cells play an important role in the pathogenesis of MS. Follicular helper T cells (Tfh) secrete IL-21 to p...

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Detalles Bibliográficos
Autores principales: Zhao, Zhihua, Mao, Zhifeng, Yin, Junjie, Shu, Yaqing, Qiu, Wei, Lu, Zhengqi, Hu, Xueqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5272958/
https://www.ncbi.nlm.nih.gov/pubmed/28149160
http://dx.doi.org/10.1016/j.sjbs.2016.08.015