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Antagonizing Retinoic Acid Receptors Increases Myeloid Cell Production by Cultured Human Hematopoietic Stem Cells

Activities of the retinoic acid receptor (RAR)α and RARγ are important to hematopoiesis. Here, we have investigated the effects of receptor selective agonists and antagonists on the primitive human hematopoietic cell lines KG1 and NB-4 and purified normal human hematopoietic stem cells (HSCs). Agoni...

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Detalles Bibliográficos
Autores principales: Brown, Geoffrey, Marchwicka, Aleksandra, Cunningham, Alan, Toellner, Kai-Michael, Marcinkowska, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5274652/
https://www.ncbi.nlm.nih.gov/pubmed/27412076
http://dx.doi.org/10.1007/s00005-016-0411-0