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Antagonizing Retinoic Acid Receptors Increases Myeloid Cell Production by Cultured Human Hematopoietic Stem Cells
Activities of the retinoic acid receptor (RAR)α and RARγ are important to hematopoiesis. Here, we have investigated the effects of receptor selective agonists and antagonists on the primitive human hematopoietic cell lines KG1 and NB-4 and purified normal human hematopoietic stem cells (HSCs). Agoni...
Autores principales: | Brown, Geoffrey, Marchwicka, Aleksandra, Cunningham, Alan, Toellner, Kai-Michael, Marcinkowska, Ewa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5274652/ https://www.ncbi.nlm.nih.gov/pubmed/27412076 http://dx.doi.org/10.1007/s00005-016-0411-0 |
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