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Neuroplastic Correlates in the mPFC Underlying the Impairment of Stress-Coping Ability and Cognitive Flexibility in Adult Rats Exposed to Chronic Mild Stress during Adolescence

Using a valid chronic mild stress (CMS) model of depression, we found that adolescent (postnatal days [PND] 28–41) CMS induced transient alterations in anhedonia that did not persist into adulthood after a 3-week recovery period. Previously stressed adult rats exhibited more immobility/despair behav...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Shao, Feng, Wang, Qiong, Xie, Xi, Wang, Weiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5274659/
https://www.ncbi.nlm.nih.gov/pubmed/28182105
http://dx.doi.org/10.1155/2017/9382797