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Hepatic caveolin‐1 is enhanced in Cyp27a1/ApoE double knockout mice

Sterol 27‐hydroxylase (CYP27A1) is involved in bile acid synthesis and cholesterol homoeostasis. Cyp27a1 ((−/−))/Apolipoprotein E ((−/−)) double knockout mice (DKO) fed a western diet failed to develop atherosclerosis. Caveolin‐1 (CAV‐1), the main component of caveolae, is associated with lipid homo...

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Detalles Bibliográficos
Autores principales: Zurkinden, Line, Mansour, Yosef T., Rohrbach, Beatrice, Vogt, Bruno, Mistry, Hiten D., Escher, Geneviève
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5275772/
https://www.ncbi.nlm.nih.gov/pubmed/28149711
http://dx.doi.org/10.1002/2211-5463.12123