Cyclic AMP Recruits a Discrete Intracellular Ca(2+) Store by Unmasking Hypersensitive IP(3) Receptors

Inositol 1,4,5-trisphosphate (IP(3)) stimulates Ca(2+) release from the endoplasmic reticulum (ER), and the response is potentiated by 3′,5′-cyclic AMP (cAMP). We investigated this interaction in HEK293 cells using carbachol and parathyroid hormone (PTH) to stimulate formation of IP(3) and cAMP, res...

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Detalles Bibliográficos
Autores principales: Konieczny, Vera, Tovey, Stephen C., Mataragka, Stefania, Prole, David L., Taylor, Colin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5276804/
https://www.ncbi.nlm.nih.gov/pubmed/28099849
http://dx.doi.org/10.1016/j.celrep.2016.12.058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5276804/
https://www.ncbi.nlm.nih.gov/pubmed/28099849
http://dx.doi.org/10.1016/j.celrep.2016.12.058

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