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HIV-1 Tat and Viral Latency: What We Can Learn from Naturally Occurring Sequence Variations

Despite the effective use of antiretroviral therapy, the remainder of a latently HIV-1-infected reservoir mainly in the resting memory CD4(+) T lymphocyte subset has provided a great setback toward viral eradication. While host transcriptional silencing machinery is thought to play a dominant role i...

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Detalles Bibliográficos
Autores principales: Kamori, Doreen, Ueno, Takamasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5276809/
https://www.ncbi.nlm.nih.gov/pubmed/28194140
http://dx.doi.org/10.3389/fmicb.2017.00080