Epigenetic Regulation of Interleukin 6 by Histone Acetylation in Macrophages and Its Role in Paraquat-Induced Pulmonary Fibrosis

Overexpression of interleukin 6 (IL-6) has been proposed to contribute to pulmonary fibrosis and other fibrotic diseases. However, the regulatory mechanisms and the role of IL-6 in fibrosis remain poorly understood. Epigenetics refers to alterations of gene expression without changes in the DNA sequ...

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Detalles Bibliográficos
Autores principales: Hu, Lingli, Yu, Yanfang, Huang, Huijie, Fan, Hanting, Hu, Li, Yin, Caiyong, Li, Kai, Fulton, David J. R., Chen, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5276821/
https://www.ncbi.nlm.nih.gov/pubmed/28194150
http://dx.doi.org/10.3389/fimmu.2016.00696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5276821/
https://www.ncbi.nlm.nih.gov/pubmed/28194150
http://dx.doi.org/10.3389/fimmu.2016.00696

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