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Sex-specific effects of serum sulfate level and SLC13A1 nonsense variants on DHEA homeostasis

CONTEXT: Sulfate is critical in the biotransformation of multiple compounds via sulfation. These compounds include neurotransmitters, proteoglycans, xenobiotics, and hormones such as dehydroepiandrosterone (DHEA). Sulfation reactions are thought to be rate-limited by endogenous sulfate concentration...

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Detalles Bibliográficos
Autores principales: Tise, Christina G., Anforth, Leslie E., Zhou, Albert E., Perry, James A., McArdle, Patrick F., Streeten, Elizabeth A., Shuldiner, Alan R., Yerges-Armstrong, Laura M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278115/
https://www.ncbi.nlm.nih.gov/pubmed/28154797
http://dx.doi.org/10.1016/j.ymgmr.2017.01.005