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Sex-specific effects of serum sulfate level and SLC13A1 nonsense variants on DHEA homeostasis

CONTEXT: Sulfate is critical in the biotransformation of multiple compounds via sulfation. These compounds include neurotransmitters, proteoglycans, xenobiotics, and hormones such as dehydroepiandrosterone (DHEA). Sulfation reactions are thought to be rate-limited by endogenous sulfate concentration...

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Detalles Bibliográficos
Autores principales:	Tise, Christina G., Anforth, Leslie E., Zhou, Albert E., Perry, James A., McArdle, Patrick F., Streeten, Elizabeth A., Shuldiner, Alan R., Yerges-Armstrong, Laura M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278115/ https://www.ncbi.nlm.nih.gov/pubmed/28154797 http://dx.doi.org/10.1016/j.ymgmr.2017.01.005

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