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Effects of a Novel Glucokinase Activator, HMS5552, on Glucose Metabolism in a Rat Model of Type 2 Diabetes Mellitus

Glucokinase (GK) plays a critical role in the control of whole-body glucose homeostasis. We investigated the possible effects of a novel glucokinase activator (GKA), HMS5552, to the GK in rats with type 2 diabetes mellitus (T2DM). Male Sprague-Dawley (SD) rats were divided into four groups: control...

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Detalles Bibliográficos
Autores principales: Wang, Ping, Liu, Huili, Chen, Li, Duan, Yingli, Chen, Qunli, Xi, Shoumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278194/
https://www.ncbi.nlm.nih.gov/pubmed/28191470
http://dx.doi.org/10.1155/2017/5812607