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Molecular Imaging Markers to Track Huntington’s Disease Pathology

Huntington’s disease (HD) is a progressive, monogenic dominant neurodegenerative disorder caused by repeat expansion mutation in the huntingtin gene. The accumulation of mutant huntingtin protein, forming intranuclear inclusions, subsequently leads to degeneration of medium spiny neurons in the stri...

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Detalles Bibliográficos
Autores principales: Wilson, Heather, De Micco, Rosa, Niccolini, Flavia, Politis, Marios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278260/
https://www.ncbi.nlm.nih.gov/pubmed/28194132
http://dx.doi.org/10.3389/fneur.2017.00011