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Modulation of actin dynamics as potential macrophage subtype-targeting anti-tumour strategy

Tumour-associated macrophages mainly comprise immunosuppressive M2 phenotypes that promote tumour progression besides anti-tumoural M1 subsets. Selective depletion or reprogramming of M2 may represent an innovative anti-cancer strategy. The actin cytoskeleton is central for cellular homeostasis and...

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Detalles Bibliográficos
Autores principales: Pergola, Carlo, Schubert, Katrin, Pace, Simona, Ziereisen, Jana, Nikels, Felix, Scherer, Olga, Hüttel, Stephan, Zahler, Stefan, Vollmar, Angelika M., Weinigel, Christina, Rummler, Silke, Müller, Rolf, Raasch, Martin, Mosig, Alexander, Koeberle, Andreas, Werz, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278352/
https://www.ncbi.nlm.nih.gov/pubmed/28134280
http://dx.doi.org/10.1038/srep41434