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Modulation of actin dynamics as potential macrophage subtype-targeting anti-tumour strategy
Tumour-associated macrophages mainly comprise immunosuppressive M2 phenotypes that promote tumour progression besides anti-tumoural M1 subsets. Selective depletion or reprogramming of M2 may represent an innovative anti-cancer strategy. The actin cytoskeleton is central for cellular homeostasis and...
Autores principales: | Pergola, Carlo, Schubert, Katrin, Pace, Simona, Ziereisen, Jana, Nikels, Felix, Scherer, Olga, Hüttel, Stephan, Zahler, Stefan, Vollmar, Angelika M., Weinigel, Christina, Rummler, Silke, Müller, Rolf, Raasch, Martin, Mosig, Alexander, Koeberle, Andreas, Werz, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278352/ https://www.ncbi.nlm.nih.gov/pubmed/28134280 http://dx.doi.org/10.1038/srep41434 |
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