Establishment and application of a novel isothermal amplification assay for rapid detection of chloroquine resistance (K76T) in Plasmodium falciparum

Chloroquine (CQ) resistance in Plasmodium falciparum is determined by the mutations in the chloroquine resistance transporter (Pfcrt) gene. The point mutation at codon 76 (K76T), which has been observed in more than 91% of P. falciparum isolates in India, is the major determinant of CQ resistance. T...

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Detalles Bibliográficos
Autores principales: Chahar, Madhvi, Mishra, Neelima, Anvikar, Anup, Dixit, Rajnikant, Valecha, Neena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278370/
https://www.ncbi.nlm.nih.gov/pubmed/28134241
http://dx.doi.org/10.1038/srep41119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278370/
https://www.ncbi.nlm.nih.gov/pubmed/28134241
http://dx.doi.org/10.1038/srep41119

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