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Signal mingle: Micropatterns of BMP-2 and fibronectin on soft biopolymeric films regulate myoblast shape and SMAD signaling

In vivo, bone morphogenetic protein 2 (BMP-2) exists both in solution and bound to the extracellular matrix (ECM). While these two modes of presentation are known to influence cell behavior distinctly, their role in the niche microenvironment and their functional relevance in the genesis of a biolog...

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Detalles Bibliográficos
Autores principales: Fitzpatrick, Vincent, Fourel, Laure, Destaing, Olivier, Gilde, Flora, Albigès-Rizo, Corinne, Picart, Catherine, Boudou, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278375/
https://www.ncbi.nlm.nih.gov/pubmed/28134270
http://dx.doi.org/10.1038/srep41479