Aqueous extract of Polygonum bistorta modulates proteostasis by ROS-induced ER stress in human hepatoma cells

Hepatocellular carcinoma (HCC) remains the leading cause of cancer mortality with limited therapeutic targets. The endoplasmic reticulum (ER) plays a pivotal role in maintaining proteostasis in normal cells. However, alterations in proteostasis are often found in cancer cells, making it a potential...

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Detalles Bibliográficos
Autores principales: Liu, Yu-Huei, Weng, Yui-Ping, Lin, Hsuan-Yuan, Tang, Sai-Wen, Chen, Chao-Jung, Liang, Chi-Jung, Ku, Chung-Yu, Lin, Jung-Yaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278379/
https://www.ncbi.nlm.nih.gov/pubmed/28134285
http://dx.doi.org/10.1038/srep41437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278379/
https://www.ncbi.nlm.nih.gov/pubmed/28134285
http://dx.doi.org/10.1038/srep41437

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