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Basophil-derived IL-6 regulates T(H)17 cell differentiation and CD4 T cell immunity
Basophils are rare, circulating granulocytes proposed to be involved in T helper (T(H)) type 2 immunity, mainly through secretion of interleukin (IL)-4. In addition to IL-4, basophils produce IL-6 and tumor necrosis factor (TNF)-α in response to immunoglobulin E (IgE) crosslinking. Differentiation o...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278410/ https://www.ncbi.nlm.nih.gov/pubmed/28134325 http://dx.doi.org/10.1038/srep41744 |