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Basophil-derived IL-6 regulates T(H)17 cell differentiation and CD4 T cell immunity

Basophils are rare, circulating granulocytes proposed to be involved in T helper (T(H)) type 2 immunity, mainly through secretion of interleukin (IL)-4. In addition to IL-4, basophils produce IL-6 and tumor necrosis factor (TNF)-α in response to immunoglobulin E (IgE) crosslinking. Differentiation o...

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Detalles Bibliográficos
Autores principales: Yuk, Chae Min, Park, Hyeung Ju, Kwon, Bo-In, Lah, Sang Joon, Chang, Jun, Kim, Ji-Young, Lee, Kyung-Mi, Park, Su-Hyung, Hong, Seokchan, Lee, Seung-Hyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278410/
https://www.ncbi.nlm.nih.gov/pubmed/28134325
http://dx.doi.org/10.1038/srep41744