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Knockdown of histidine-rich calcium-binding protein (HRC) suppresses liver fibrosis by inhibiting the activation of hepatic stellate cells

The histidine-rich calcium-binding protein (HRC) is a regulator of Ca(2+) homeostasis and it plays a significant role in hepatocellular carcinoma (HCC) progression. However, the relationship between HRC and liver fibrogenesis is still unknown. Our data demonstrates that HRC was upregulated in fibrot...

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Detalles Bibliográficos
Autores principales: Liu, Jingmei, Li, Mengke, Gong, Jin, Han, Ping, Wang, Yunwu, Li, Dongxiao, Tian, Dean, Liao, Jiazhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278420/
https://www.ncbi.nlm.nih.gov/pubmed/27881436
http://dx.doi.org/10.1242/bio.019828