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Gene silencing of Nox4 by CpG island methylation during hepatocarcinogenesis in rats

The association between the downregulation of genes and DNA methylation in their CpG islands has been extensively studied as a mechanism that favors carcinogenesis. The objective of this study was to analyze the methylation of a set of genes selected based on their microarray expression profiles dur...

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Detalles Bibliográficos
Autores principales: López-Álvarez, Guadalupe S., Wojdacz, Tomasz K., García-Cuellar, Claudia M., Monroy-Ramírez, Hugo C., Rodríguez-Segura, Miguel A., Pacheco-Rivera, Ruth A., Valencia-Antúnez, Carlos A., Cervantes-Anaya, Nancy, Soto-Reyes, Ernesto, Vásquez-Garzón, Verónica R., Sánchez-Pérez, Yesennia, Villa-Treviño, Saúl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278421/
https://www.ncbi.nlm.nih.gov/pubmed/27895046
http://dx.doi.org/10.1242/bio.020370